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Prof. Paulo Marcos Donate

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For the complete CV, click here
E-mail: pmdonate@usp.br

Prof. Paulo Marcos Donate got his degree in Chemistry at the University of São Paulo in 1978. Under the supervision of prof. Mauricio Gomes Constantino, prof. Constantino concluded his Ph.D. in 1984 on organic synthesis at the University of São Paulo USP). In 1986, he started a post-doctoral fellowship at entre de Recherches de Carrières-Rhône Poulenc, CRC, França. In 1987, prof. Donate got a post-doctoral fellowship position at Unité Mixte Cnrs Rhône Poulenc, CNRS/RP, França. After three years working at Roché (1990-1993),  he started his research and teaching activities at the Department of Chemistry at FFCLRP, USP in the Ribeirão Preto city. There, his experience in the field of organic synthesis has been crucial for the Laboratory of Organic Synthesis (LOS), which he helped to create.   

          Over almost three decades as a member (and currently the head) of the Laboratory of Organic Synthesis (LOS), prof. Donate published about 70 scientific papers in the fields of organic synthesis, nuclear magnetic resonance, and biological activities of synthetic and semi-synthetic organic compounds. Part of his research was dedicated to the development of novel methodologies for the synthesis of lactones, including one-pot multicomponent reactions (MCR). He also shared his large experience in these fields by writing three textbooks. 
           Prof. Donate spends his time outside the lab playing soccer and tennis and enjoying his time with other chemists appreciating a good beer. He has a good sense of humor and students love to meet him at the department halls or even in the LOS to have some minutes of chat. Prof. Donate brings light and inspiration to LOS students and colleagues in love with Organic Chemistry.

       Some selected publications

 

       Silva, W. R.; Matsubara, E. Y.; Rosolen, J. M.; Donate, P. M.; Gunnella, R. Pd catalysts supported on different hydrophilic or hydrophobic carbonaceous substrates for furfural and 5-(hydroxymethyl)-furfural hydrogenation in water. Molecular Catalysis 2021, 504, 111496-111496.

     Baviera, G. S.; Donate, P. M. Recent advances in the synthesis of anthracene derivatives. Beilstein Journal of Organic Chemistry 2021, 17, 2028-2050. 

     Previdi, D.; Rodrigues, S. M. M.; Coelho, M. G.; Candido, A. C. B. B.; Magalhães, L. G.; Donate, P. M. Synthesis and antileishmanial activity of some functionalized peptoids. Journal of the Brazilian Chemical Society 2019, 30, 1334-1340. 

    Rodrigues, S. M. M.; Previdi, D.; Baviera, G. S.; Matias, A. A.; Donate, P. MNiobium pentachloride mediated (Hetero)aromatic aldehyde Friedel-Crafts hydroxyalkylation with arenes: an efficient strategy to synthesize triarylmethanes. Synthesis 2019, 51, 4498-4506.

    Abd El-Salam, M.; Bastos, J. K.; Han, J. J.; Previdi, D.; Coelho, E. B.; Donate, P. M.; Romero, M. F.; Lieske, J. The synthesized plant metabolite 3,4,5-tri-O-galloylquinic acid methyl ester inhibits calcium oxalate crystal growth in a Drosophila model, downregulates renal cell surface annexin A1 expression, and decreases crystal adhesion to cells. Journal of Medicinal Chemistry 2018, 6, 1609-1621.

     Previdi, D.; Nardini, V.; Rosa, M. E.; Palaretti, V.; Da Silva, G. V. J.; Donate, P. M. Stereochemical assignment of four diastereoisomers of a maculalactone derivative by computational NMR calculations. Journal of Molecular Structure 2018, 1178, 467-478.

      Del Ponte, G.; Archanjo, F. C.; Watanabe, L. Y.; Donate, P. M.; Campos, J. M. Syntheses of non-aromatic medium and large rings synthesized via phenylnitrenium ions. Arabian Journal of Chemistry 2016, 11, 415-425.

       Pinatto-Botelho, M.; Donate, P. M. A rapid protocol to synthesize γ-butirolactone derivatives via the microwave technique. Current Microwave Chemistry 2015, 2, 83-87.

     Silva, E. H. B.; Emery, F. S.; Ponte, G. D.; Donate, P. M. Synthesis of some functionalized peptomers via Ugi four-component reaction. Synthetic Communications 2015, 45, 1761-1767.

        Frederico, D.; Donate, P. M.; Bronze, E. S.; Constantino, M. G.; Bronze, E. S.; Sairre, M. I. A short and efficient synthesis of crocetin-dimethylester and crocetindial. Journal of Organic Chemistry, 2003, 68, 9126-9128.

Books

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Constantino, M. G.; Silva, G. V. J.; Donate, P. M. Fundamentos de Química Experimental. 2. ed. São Paulo: Edusp-Editora da Universidade de São Paulo, 2011. v. 1. 272p 
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Donate, P. M. (org). Estrutura e propriedade dos compsotso orgânics. São Paulo: Editora Atheneu, 2016. 407 p. 
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